NICE NG206 Differential Diagnosis
NICE-compliant investigations to exclude other diagnoses when ME/CFS is suspected
Red Flag Symptoms
Check any symptoms present that may require urgent evaluation
Infectious/Inflammatory
Malignancy/Metabolic
Cardiovascular
Cardiopulmonary
Neurological
Hematological
Infectious/Malignancy
Hepatic
NICE NG206 Required Investigations
Mandatory tests to exclude other diagnoses when ME/CFS is suspected
Required investigations for all patients with suspected ME/CFS
Urinalysis for protein, blood and glucose, Full blood count, Urea and electrolytes + 9 more
Consider based on clinical presentation and history
Vitamin D, Vitamin B12 and folate levels, Serological tests if infection history + 1 more
Extra considerations for children and young people
Growth parameters, Developmental assessment, School attendance review + 1 more