Medical Disclaimer: This tool provides educational information about POTS phenotypes only. It does not provide medical advice, diagnosis, or treatment recommendations. Treatment decisions must be made by qualified healthcare providers. Do not start, stop, or change any medication based on this information.

POTS Subtype & Treatment Advisor

Determine POTS subtype for personalized treatment recommendations

Patient Information

Basic patient details for treatment planning

Age

Relevant Comorbidities (check all that apply)

Diabetes

Autoimmune Disease

EDS

MCAS

Hypovolemic POTS

Low blood volume causing orthostatic intolerance

Low-normal blood pressure (<110/70)

Excessive thirst

Salt craving

Signs of volume depletion

Elevated renin/aldosterone (if available)

Score: 0/5 Criteria met

Neuropathic POTS

Peripheral autonomic neuropathy affecting blood vessel control

Distal small fiber neuropathy symptoms

GI dysfunction (gastroparesis, constipation)

Anhidrosis or reduced sweating

Pupillary abnormalities

History of diabetes or autoimmune disease

Score: 0/5 Criteria met

Hyperadrenergic POTS

Excessive sympathetic nervous system activation

Hypertension when standing

Anxiety, panic attacks, tremor

Migraine headaches

Cold hands and feet

Elevated standing norepinephrine >600 pg/mL

Score: 0/5 Criteria met

Autoimmune POTS

Autoimmune-mediated autonomic dysfunction

Personal/family history of autoimmune disease

Rapid onset of symptoms

Viral illness trigger (EBV, COVID, etc.)

Positive autonomic antibodies (if tested)

Other autoimmune markers positive

Score: 0/5 Criteria met

About InvisibleDx

InvisibleDx is an open-source educational tool for learning about ME/CFS, Long COVID, and POTS criteria. Designed exclusively for healthcare education and research purposes - NOT for patient care or medical use.

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Nordjysk Speciallægeklinik
by Humanstack

Educational Tool Only: Educational simulation based on peer-reviewed literature. Training data for educational purposes only. This tool is NOT validated for clinical use and must NOT be used for patient care or medical decisions.